No. Laboratory results are interpreted with symptoms, medical history, sampling conditions, and related tests.
Information about a laboratory test
Low Apolipoprotein A1: What Does It Mean?
Low ApoA1 can be associated with lower HDL-related capacity and increased cardiovascular risk.
Test summary
- Test name
- Apolipoprotein A1
- Abbreviations
- ApoA1, ApoA-I
- Category
- Cardiometabolic / Advanced Lipids
- Panel
- Advanced Lipid / Cardiovascular Risk
- Specimen
- Serum
- Common units
- mg/dL, g/L
What does the test measure?
Measures apolipoprotein A1, the main structural protein of HDL particles.
Why is the test ordered?
Used in selected advanced lipid assessments, alongside HDL or as part of an ApoB/ApoA1 ratio.
Information about a low result
Low ApoA1 can be associated with lower HDL-related capacity and increased cardiovascular risk.
Information about a high result
High ApoA1 often accompanies higher HDL but does not by itself guarantee cardiovascular protection.
Reference and clinical context
Use the laboratory report as context, but treatment goals and risk thresholds vary with age, cardiovascular risk, diabetes, kidney disease, and current therapy.
Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.
Interpretation notes
ApoA1 reference information can vary by sex and age and is often interpreted with ApoB.
Related specialties
- Cardiology
- Internal Medicine
- Endocrinology
- Family Medicine
- Pediatric Cardiology
Frequently asked questions
Sources
Apolipoprotein B, Serum — Mayo Clinic Laboratories
Reference laboratory test catalog · 2026 · Age-specific ApoB categories and interpretation · Verified: Aug 12, 2026
Apolipoprotein A1, Serum — Mayo Clinic Laboratories
Reference laboratory test catalog · 2026 · Sex- and age-specific ApoA1 reference information and ApoB/ApoA1 context · Verified: Aug 12, 2026
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