Information about a laboratory test
Positive leukocyte esterase suggests white blood cells in urine; causes other than infection and contamination are also possible.
The Leukocyte Esterase test assesses leukocyte esterase activity that suggests white blood cells in urine.
It is used to screen for white blood cells and possible urinary tract infection.
A negative leukocyte esterase result is generally expected but does not completely exclude infection.
Positive leukocyte esterase suggests white blood cells in urine; causes other than infection and contamination are also possible.
Start with the performing laboratory's reference interval, method, collection conditions and reporting unit. Urinalysis findings do not establish a diagnosis on their own.
Sourced reference context for Leukocyte Esterase
This is sourced example reference/clinical-context information; the user's own laboratory report and specimen conditions take priority.
Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.
Start with the performing laboratory's reference interval, method, collection conditions and reporting unit. Urinalysis findings do not establish a diagnosis on their own. Interpretation may be more informative when related urine parameters are considered together.
Urinalysis — U.S. National Library of Medicine (MedlinePlus)
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Leukocyte esterase urine test — U.S. National Library of Medicine (MedlinePlus)
Government medical reference · 2025 · Leukocyte esterase and WBC/UTI screening · Verified: Aug 12, 2026
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