Information about a laboratory test

High MCHC: What Does It Mean?

A high MCHC can occur in some conditions such as hemolytic anemia or hereditary spherocytosis; technical or specimen-related effects also need consideration.

Test summary

Test name
MCHC
Abbreviations
MCHC
Category
Hematology
Panel
RBC Indices / Hemogram
Specimen
Whole blood
Common units
g/dL

What does the test measure?

Shows the average concentration of hemoglobin within red blood cells.

Why is the test ordered?

Provides information about hemoglobin concentration in red blood cells and contributes to the assessment of anemia patterns.

Information about a low result

A low MCHC may occur in hypochromic patterns such as iron deficiency or thalassemia.

Information about a high result

A high MCHC can occur in some conditions such as hemolytic anemia or hereditary spherocytosis; technical or specimen-related effects also need consideration.

Reference and clinical context

Use the reference interval printed on your own laboratory report first. Reference intervals may vary by laboratory, method, unit, age, sex, pregnancy, specimen, and other conditions. Numeric records in this workbook are explicitly labeled as either source-based example reference intervals or clinical decision cutoffs.

Reference range 1

>= 32 – <= 36 g/dL

Population
General
Specimen
Whole blood

Example reference interval

MedlinePlus example.

Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.

Interpretation notes

A high MCHC can occur in conditions such as hemolytic anemia or hereditary spherocytosis; laboratory or specimen-related effects should also be excluded.

Related specialties

  • Hematology
  • Internal Medicine

Frequently asked questions

Sources

  1. CBC blood test — U.S. National Library of Medicine (MedlinePlus)

    Government medical reference · 2024 · CBC components; example adult reference ranges; high/low RBC, WBC and platelet context · Verified: Aug 11, 2026

  2. Red Blood Cell (RBC) Indices — U.S. National Library of Medicine (MedlinePlus)

    Government medical reference · 2024 · MCV, MCH, MCHC, RDW definitions and interpretation · Verified: Aug 11, 2026