Low AST is usually not clinically important on its own and is interpreted in laboratory context.
Test summary
Test name
AST
Abbreviations
AST, ASAT, GOT
Category
Hepatology / Liver Enzymes
Panel
Liver Function Panel
Specimen
Serum / plasma
Common units
U/L, µkat/L
What does the test measure?
Measures blood activity of AST, an enzyme found in the liver, muscles and several other tissues.
Why is the test ordered?
Usually ordered with ALT and other liver tests; AST can also be affected by injury outside the liver.
Information about a low result
Low AST is usually not clinically important on its own and is interpreted in laboratory context.
Information about a high result
High AST can occur with liver, muscle or other tissue injury; the pattern with ALT and related tests helps interpretation.
Reference and clinical context
Start with the performing laboratory's reference interval, unit and specimen conditions. Numeric information on this page is stored as sourced example intervals or clinical thresholds.
Reference range 1
>= 8 – <= 33 U/L
Population
Adults
Age range
18
Specimen
Serum / plasma
Example adult AST reference interval
The source presents these values as a common example reference interval. Laboratory method, age and clinical context can change the range; the user's own report takes priority.
Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.
Interpretation notes
AST is not liver-specific. It should be interpreted particularly with ALT and the clinical context.
Related specialties
Gastroenterology
Internal Medicine
Family Medicine
Frequently asked questions
No. Laboratory results are interpreted with symptoms, medical history, specimen conditions and related tests.
Start with the performing laboratory's own reference interval; clinical cutoffs, when relevant, are separate sourced thresholds used for a specific purpose.
Results that are clearly outside range, persistent, symptomatic or unexpected should be reviewed by a healthcare professional.
Government medical reference · 2026 · Example adult intervals for ALT, AST, ALP, albumin, bilirubin, total protein, BUN, creatinine and electrolytes · Verified: Aug 12, 2026
ALT Blood Test — U.S. National Library of Medicine (MedlinePlus)
Government medical reference · 2026 · ALT purpose, liver-cell injury context and example interval · Verified: Aug 12, 2026
AST Test — U.S. National Library of Medicine (MedlinePlus)
Government medical reference · 2026 · AST purpose and interpretation with ALT/other liver tests · Verified: Aug 12, 2026