Information about a laboratory test

Amylase: Low Result: What Does It Mean?

Low amylase may occur in some chronic pancreatic disorders or when pancreatic function is markedly reduced, but it does not diagnose pancreatic insufficiency by itself.

Test summary

Test name
Amylase
Abbreviations
AMY
Category
Pancreatic / Digestive Enzymes
Panel
Pancreatic Assessment
Specimen
Serum / plasma
Common units
U/L

What does the test measure?

The Amylase test measures the level of amylase, a carbohydrate-digesting enzyme produced mainly by the pancreas and salivary glands.

Why is the test ordered?

It is used especially when acute pancreatitis or other pancreatic disorders are suspected; amylase and lipase are often interpreted together with clinical findings.

Information about a low result

Low amylase may occur in some chronic pancreatic disorders or when pancreatic function is markedly reduced, but it does not diagnose pancreatic insufficiency by itself.

Information about a high result

High amylase may occur with acute pancreatitis, salivary-gland disorders, pancreatic or bile-duct obstruction and other conditions; lipase provides additional pancreatic context.

Reference and clinical context

Start with the performing laboratory's reference interval, unit, specimen type and method. Numeric information on this page is stored as sourced example intervals or clinical thresholds.

Reference range 1

>= 40 – <= 140 U/L

Population
Adults / general laboratory example
Age range
18
Specimen
Serum / plasma

Example serum amylase reference interval

This is sourced reference/clinical-context information and should not be used alone as a diagnosis or treatment decision. The laboratory report, medication use and clinical context take priority.

Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.

Interpretation notes

Amylase also comes from salivary glands. In suspected pancreatitis, lipase generally provides more pancreas-specific information; results are interpreted with symptoms and imaging.

Related specialties

  • Gastroenterology
  • Internal Medicine
  • Emergency Medicine
  • General Surgery

Frequently asked questions

Sources

  1. Amylase Test — U.S. National Library of Medicine (MedlinePlus)

    Government medical reference · 2024 · Amylase testing and pancreatic/salivary interpretation · Verified: Aug 12, 2026

  2. Amylase - blood — U.S. National Library of Medicine (MedlinePlus)

    Government medical encyclopedia · 2025 · Example 40–140 U/L serum amylase reference interval · Verified: Aug 12, 2026

  3. Lipase Tests — U.S. National Library of Medicine (MedlinePlus)

    Government medical reference · 2025 · Lipase testing and pancreatic interpretation · Verified: Aug 12, 2026