Information about a laboratory test
The LDH test measures the blood level of lactate dehydrogenase, an enzyme present in many tissues.
The LDH test measures the blood level of lactate dehydrogenase, an enzyme present in many tissues.
It is used as a broad marker of possible tissue injury but does not identify the injured organ or cause by itself.
A low value is usually not interpreted as a clinical problem by itself; the purpose of testing and laboratory context matter.
High LDH can occur with cell or tissue damage but does not identify the source; hemolysis, liver, muscle, lung and many other conditions can affect it.
Start with the performing laboratory's reference interval, unit, specimen type and method. Numeric information on this page is stored as sourced example intervals or clinical thresholds.
>= 125 – <= 220 U/L
Example LDH reference interval
This is sourced reference/clinical-context information and should not be used alone as a diagnosis or treatment decision. The laboratory report, medication use and clinical context take priority.
Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.
LDH can come from many tissues, and hemolysis of the blood sample can falsely increase it. Other tests and sometimes LDH isoenzymes are needed to localize the source.
Creatine Kinase — U.S. National Library of Medicine (MedlinePlus)
Government medical reference · 2023 · CK testing, muscle injury and CK isoenzyme context · Verified: Aug 12, 2026
Lactate Dehydrogenase (LDH) Test — U.S. National Library of Medicine (MedlinePlus)
Government medical reference · 2023 · LDH testing and nonspecific tissue-damage interpretation · Verified: Aug 12, 2026
Lactate dehydrogenase test — U.S. National Library of Medicine (MedlinePlus)
Government medical encyclopedia · 2026 · Example 125–220 U/L LDH reference interval · Verified: Aug 12, 2026
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