Information about a laboratory test

High uACR: What Does It Mean?

High UACR can indicate albumin leakage from the kidneys; exercise, infection and temporary conditions can affect results, so repeat testing may be needed.

Test summary

Test name
uACR
Abbreviations
UACR, ACR, Microalbumin/Creatinine Ratio
Category
Nephrology / Albuminuria
Panel
Kidney Damage Assessment
Specimen
Spot urine
Common units
mg/g, mg/mmol

What does the test measure?

Assesses urine albumin loss by comparing albumin with creatinine in a spot urine sample.

Why is the test ordered?

Used with eGFR to screen and monitor kidney damage, especially in people with risks such as diabetes or hypertension.

Information about a low result

A low/normal UACR generally indicates less albumin leakage, but kidney assessment should not rely on this test alone.

Information about a high result

High UACR can indicate albumin leakage from the kidneys; exercise, infection and temporary conditions can affect results, so repeat testing may be needed.

Reference and clinical context

Start with the performing laboratory's reference interval, unit and specimen conditions. Numeric information on this page is stored as sourced example intervals or clinical thresholds.

Reference context 1

< 30 mg/g

Population
Adults / albuminuria classification
Age range
18
Specimen
Spot urine

A1: normal to mildly increased

This is one of the albuminuria A categories used in CKD assessment. Interpret it with eGFR and chronicity; a single abnormal measurement may need confirmation.

Reference context 2

>= 30 – <= 300 mg/g

Population
Adults / albuminuria classification
Age range
18
Specimen
Spot urine

A2: moderately increased

This is one of the albuminuria A categories used in CKD assessment. Interpret it with eGFR and chronicity; a single abnormal measurement may need confirmation.

Reference context 3

> 300 mg/g

Population
Adults / albuminuria classification
Age range
18
Specimen
Spot urine

A3: severely increased

This is one of the albuminuria A categories used in CKD assessment. Interpret it with eGFR and chronicity; a single abnormal measurement may need confirmation.

Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.

Interpretation notes

UACR and eGFR complement each other in CKD risk classification. One abnormal measurement does not prove chronic disease.

Related specialties

  • Nephrology
  • Endocrinology
  • Internal Medicine
  • Family Medicine

Frequently asked questions

Sources

  1. Albumin Blood (Serum) Test — U.S. National Library of Medicine (MedlinePlus)

    Government medical reference · 2026 · Albumin meaning and adult example interval · Verified: Aug 12, 2026

  2. Creatinine Test — U.S. National Library of Medicine (MedlinePlus)

    Government medical reference · 2026 · Creatinine limitations and use with eGFR, BUN and urine testing · Verified: Aug 12, 2026

  3. Chronic Kidney Disease Tests & Diagnosis — National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    U.S. government medical reference · 2026 · eGFR and urine albumin/UACR as key kidney tests; broad interpretation thresholds · Verified: Aug 12, 2026

  4. How to Classify CKD — National Kidney Foundation

    Professional clinical reference · 2026 · G1-G5 eGFR categories and A1-A3 albuminuria categories · Verified: Aug 12, 2026