Information about a laboratory test
The hs-CRP test measures very low CRP concentrations using a high-sensitivity assay.
The hs-CRP test measures very low CRP concentrations using a high-sensitivity assay.
It is used to measure low-grade inflammation more sensitively and, in appropriate patients, add information to cardiovascular risk assessment.
A low value is usually not interpreted as a clinical problem by itself; the purpose of testing and laboratory context matter.
High hs-CRP can reflect low-grade inflammatory burden. For cardiovascular risk it is interpreted with other risk factors, while acute infection or marked inflammation can temporarily raise the result.
Start with the performing laboratory's reference interval, unit, specimen type and method. Numeric information on this page is stored as sourced example intervals or clinical thresholds.
>= 2 mg/L
hs-CRP threshold used as an ASCVD risk-enhancing factor
This is sourced reference/clinical-context information and should not be used alone as a diagnosis or treatment decision. The laboratory report, medication use and clinical context take priority.
Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.
hs-CRP measures the same protein as standard CRP at lower concentrations, but the clinical use differs. Acute inflammation can make cardiovascular-risk interpretation inappropriate.
C-Reactive Protein (CRP) Test — U.S. National Library of Medicine (MedlinePlus)
Government medical reference · 2025 · CRP testing, inflammation and nonspecific interpretation · Verified: Aug 12, 2026
Prioritizing Health | hsCRP: A Promising Risk Assessment Tool — American College of Cardiology
Professional cardiovascular reference · 2025 · hsCRP cardiovascular risk context including ≥2 mg/L risk-enhancing threshold · Verified: Aug 12, 2026
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