Information about a laboratory test
High direct bilirubin can occur when bilirubin excretion through bile is impaired in hepatobiliary conditions.
Measures the conjugated fraction of bilirubin in blood after processing by the liver.
Used to fractionate an elevated total bilirubin and help characterize liver or bile-duct-related patterns.
Low direct bilirubin is usually not clinically concerning.
High direct bilirubin can occur when bilirubin excretion through bile is impaired in hepatobiliary conditions.
Start with the performing laboratory's reference interval, unit and specimen conditions. Numeric information on this page is stored as sourced example intervals or clinical thresholds.
< 0.3 mg/dL
Example direct bilirubin upper limit
The source presents these values as a common example reference interval. Laboratory method, age and clinical context can change the range; the user's own report takes priority.
Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.
Direct bilirubin should be interpreted with total bilirubin and other liver tests; it is not diagnostic by itself.
Bilirubin Blood Test — U.S. National Library of Medicine (MedlinePlus)
Government medical reference · 2026 · Total/direct bilirubin meaning, jaundice context and example intervals · Verified: Aug 12, 2026
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