Information about a laboratory test

High Ceruloplasmin: What Does It Mean?

High ceruloplasmin can occur with inflammation, pregnancy/estrogen effects and other contexts; copper results provide additional information.

Test summary

Test name
Ceruloplasmin
Abbreviations
CP, Ceruloplasmin
Category
Copper Metabolism / Proteins
Panel
Copper Metabolism Evaluation
Specimen
Serum / plasma
Common units
mg/dL, g/L

What does the test measure?

The Ceruloplasmin test measures the blood protein ceruloplasmin that carries most circulating copper.

Why is the test ordered?

Ordered when trace-mineral deficiency or excess is suspected, with malabsorption or in selected clinical contexts; timing and inflammation can affect some measurements.

Information about a low result

Low ceruloplasmin can occur with disorders of copper handling, malnutrition/malabsorption or some liver/kidney conditions; it does not diagnose Wilson disease by itself.

Information about a high result

High ceruloplasmin can occur with inflammation, pregnancy/estrogen effects and other contexts; copper results provide additional information.

Reference and clinical context

Start with the performing laboratory's reference interval, unit, specimen type and method. Numeric information on this page is stored as sourced example intervals or clinical thresholds.

Reference range 1

>= 20 – <= 40 mg/dL

Population
Adults
Age range
18
Specimen
Serum

Sourced example reference interval for Ceruloplasmin

This is a sourced example reference interval; laboratory, method, age and clinical context can change the range. The user's own report takes priority.

Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.

Interpretation notes

Ceruloplasmin carries most circulating copper. Diagnostic interpretation may require serum/urine copper, symptoms and family history.

Related specialties

  • Internal Medicine
  • Family Medicine
  • Endocrinology

Frequently asked questions

Sources

  1. Copper – Health Professional Fact Sheet — NIH Office of Dietary Supplements

    U.S. government nutrition reference · 2022 · Copper biology, deficiency and zinc-copper interaction · Verified: Aug 12, 2026

  2. Ceruloplasmin Test — U.S. National Library of Medicine (MedlinePlus)

    Government medical reference · 2023 · Ceruloplasmin, copper metabolism and Wilson disease testing limitations · Verified: Aug 12, 2026

  3. Ceruloplasmin Blood Test — U.S. National Library of Medicine (MedlinePlus)

    Government medical reference · 2025 · Example adult ceruloplasmin reference interval · Verified: Aug 12, 2026