High BUN can occur with reduced kidney function, dehydration, increased protein breakdown or gastrointestinal bleeding.
Test summary
Test name
BUN
Abbreviations
BUN
Category
Nephrology / Nitrogen Waste
Panel
Renal Function / Basic Metabolic Panel
Specimen
Serum / plasma
Common units
mg/dL, mmol/L
What does the test measure?
Measures the amount of nitrogen in blood that comes from urea, a waste product of protein metabolism.
Why is the test ordered?
Commonly interpreted with creatinine to help assess kidney function, hydration and selected metabolic contexts.
Information about a low result
Low BUN can occur with low protein intake, excess body water or severe impairment of liver urea production, among other causes.
Information about a high result
High BUN can occur with reduced kidney function, dehydration, increased protein breakdown or gastrointestinal bleeding.
Reference and clinical context
Start with the performing laboratory's reference interval, unit and specimen conditions. Numeric information on this page is stored as sourced example intervals or clinical thresholds.
Reference range 1
>= 6 – <= 20 mg/dL
Population
Adults
Age range
18
Specimen
Serum / plasma
Example adult BUN reference interval
The source presents these values as a common example reference interval. Laboratory method, age and clinical context can change the range; the user's own report takes priority.
Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.
Interpretation notes
BUN is not kidney-specific. Creatinine, eGFR, hydration and the clinical context should be considered together.
Related specialties
Nephrology
Internal Medicine
Family Medicine
Frequently asked questions
No. Laboratory results are interpreted with symptoms, medical history, specimen conditions and related tests.
Start with the performing laboratory's own reference interval; clinical cutoffs, when relevant, are separate sourced thresholds used for a specific purpose.
Results that are clearly outside range, persistent, symptomatic or unexpected should be reviewed by a healthcare professional.
Government medical reference · 2026 · Example adult intervals for ALT, AST, ALP, albumin, bilirubin, total protein, BUN, creatinine and electrolytes · Verified: Aug 12, 2026
Creatinine Test — U.S. National Library of Medicine (MedlinePlus)
Government medical reference · 2026 · Creatinine limitations and use with eGFR, BUN and urine testing · Verified: Aug 12, 2026
BUN - Blood Test — U.S. National Library of Medicine (MedlinePlus)
Government medical reference · 2026 · BUN meaning, kidney/liver/hydration context and example interval · Verified: Aug 12, 2026