Information about a laboratory test

Fructosamine: What Does This Test Measure?

Measures glycated serum proteins and reflects glucose exposure over roughly the previous 2–3 weeks.

Test summary

Test name
Fructosamine
Abbreviations
Fructosamine, Glycated Serum Protein
Category
Endocrinology / Glucose Metabolism
Panel
Short-Term Glycemic Monitoring
Specimen
Serum
Common units
µmol/L

What does the test measure?

Measures glycated serum proteins and reflects glucose exposure over roughly the previous 2–3 weeks.

Why is the test ordered?

May be used when A1C is unreliable or when a shorter-term view of glycemic change is useful.

Information about a low result

Low fructosamine can reflect lower glucose exposure but may also be affected by low serum-protein concentrations.

Information about a high result

High fructosamine may reflect higher glucose exposure over recent weeks; serum-protein status can influence the result.

Reference and clinical context

Use the performing laboratory's report and the sampling conditions first. Fasting status, timing, and whether the test is diagnostic or for monitoring can change interpretation.

Reference range 1

>= 200 – <= 285 µmol/L

Population
General
Specimen
Serum

Example reference interval

The source laboratory gives >=200–<=285 µmol/L as an example interval. Use the performing laboratory's own reference interval for an individual result.

Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.

Interpretation notes

Fructosamine covers a shorter time window than A1C. Albumin/protein changes and assay method can affect interpretation.

Related specialties

  • Endocrinology
  • Internal Medicine
  • Family Medicine
  • Pediatric Endocrinology

Frequently asked questions

More information about this test

Sources

  1. The A1C Test & Diabetes — National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    U.S. government medical reference · 2026 · A1C meaning, diagnostic use, pregnancy and hemoglobin-related limitations · Verified: Aug 12, 2026

  2. The A1C Test & Race/Ethnicity — National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

    U.S. government medical reference · 2026 · Fructosamine as a shorter-term glycemic marker when A1C may be unreliable · Verified: Aug 12, 2026

  3. Fructosamine, Serum — Mayo Clinic Laboratories

    Reference laboratory test catalog · 2026 · Example fructosamine reference interval and short-term glycemic context · Verified: Aug 12, 2026