Information about a laboratory test

CA 15-3 High Result: What Does It Mean?

A high tumor marker does not diagnose cancer on its own; benign conditions and other causes can also raise the level.

Test summary

Test name
CA 15-3
Abbreviations
CA 15-3, CA15-3
Category
Tumor Markers / Oncology
Panel
Tumor Marker Monitoring
Specimen
Serum / plasma
Common units
U/mL

What does the test measure?

CA 15-3 measures the relevant tumor marker in blood.

Why is the test ordered?

CA 15-3 may be used with other clinical information for especially monitoring treatment response and disease course in advanced breast cancer.

Information about a low result

A low/normal tumor marker does not rule out cancer by itself.

Information about a high result

A high tumor marker does not diagnose cancer on its own; benign conditions and other causes can also raise the level.

Reference and clinical context

Start with the performing laboratory's reference or decision range, assay method, specimen and reporting unit. A single result usually does not establish a diagnosis on its own.

Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.

Interpretation notes

Tumor markers are often more useful for monitoring known disease and selected clinical evaluations than as stand-alone diagnostic tests.

Related specialties

  • Oncology
  • Internal Medicine

Frequently asked questions

Sources

  1. Tumor Marker Tests — U.S. National Library of Medicine (MedlinePlus)

    Government medical reference · 2025 · General tumor marker uses and limitations, including CA 15-3 · Verified: Aug 12, 2026

  2. Tumor Marker Tests in Common Use — National Cancer Institute

    U.S. government cancer reference · 2023 · Common tumor markers and typical monitoring uses · Verified: Aug 12, 2026