Information about a laboratory test

Anti-HCV What Does This Test Mean?

Anti-HCV checks for antibodies to hepatitis C virus in blood.

Test summary

Test name
Anti-HCV
Abbreviations
anti-HCV, HCV Ab
Category
Infectious Disease / Hepatology
Panel
Hepatitis C Screening
Specimen
Serum / plasma
Common units
qualitative, index

What does the test measure?

Anti-HCV checks for antibodies to hepatitis C virus in blood.

Why is the test ordered?

Anti-HCV is used as an initial screening test for HCV infection.

Information about a low result

A negative/nonreactive anti-HCV result usually means HCV antibody was not detected; recent exposure may require attention to the window period.

Information about a high result

A positive/reactive anti-HCV result can reflect past or current HCV infection; HCV RNA testing is needed to determine current infection.

Reference and clinical context

Start with the performing laboratory's reference or decision range, assay method, specimen and reporting unit. A single result usually does not establish a diagnosis on its own.

Reference range 1

Population
General screening context
Specimen
Serum / plasma
Method
Antibody assay

Sourced reference/decision context for Anti-HCV

This is sourced reference or clinical-context information; the user's own laboratory report, assay method and clinical context take priority.

Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.

Interpretation notes

An HCV antibody test does not confirm active infection by itself; a reactive result is followed by HCV RNA testing.

Related specialties

  • Infectious Disease
  • Gastroenterology
  • Internal Medicine

Frequently asked questions

More information about this test

Sources

  1. Clinical Testing and Diagnosis for Hepatitis B — Centers for Disease Control and Prevention

    U.S. government clinical guidance · 2025 · HBsAg, anti-HBs, total anti-HBc triple-panel interpretation · Verified: Aug 12, 2026

  2. Testing for Hepatitis C — Centers for Disease Control and Prevention

    U.S. government clinical reference · 2025 · HCV antibody screening and follow-up HCV RNA testing · Verified: Aug 12, 2026

  3. Getting Tested for HIV — Centers for Disease Control and Prevention

    U.S. government clinical reference · 2025 · HIV antigen/antibody testing and window period · Verified: Aug 12, 2026