ALP can be physiologically higher in children because of growth and bone formation, so an age-appropriate pediatric reference interval is needed.
Test summary
Test name
ALP
Abbreviations
ALP, ALKP
Category
Hepatology / Bone & Cholestatic Enzymes
Panel
Liver Function Panel / Bone Metabolism
Specimen
Serum / plasma
Common units
U/L, µkat/L
What does the test measure?
Measures alkaline phosphatase enzyme activity in blood; major clinical sources include liver/bile ducts and bone.
Why is the test ordered?
Used to assess hepatobiliary and bone-related conditions, often together with GGT and other tests.
Information about a low result
Low ALP is less common and may be associated with nutritional, mineral or other conditions; it is not diagnostic by itself.
Information about a high result
High ALP may be hepatobiliary or bone-related. Physiologic elevations can also occur during growth in children and in pregnancy.
Reference and clinical context
Start with the performing laboratory's reference interval, unit and specimen conditions. Numeric information on this page is stored as sourced example intervals or clinical thresholds.
Reference range 1
>= 20 – <= 130 U/L
Population
Adults
Age range
18
Specimen
Serum / plasma
Example adult ALP reference interval
The source presents these values as a common example reference interval. Laboratory method, age and clinical context can change the range; the user's own report takes priority.
Reference ranges may vary by laboratory, method used, age, sex, pregnancy status, and clinical context. The reference range on your own laboratory report takes precedence.
Interpretation notes
GGT, other liver tests and sometimes ALP isoenzymes help identify the likely source. Age and pregnancy can change interpretation.
Related specialties
Gastroenterology
Internal Medicine
Pediatrics
Endocrinology
Frequently asked questions
No. Laboratory results are interpreted with symptoms, medical history, specimen conditions and related tests.
Start with the performing laboratory's own reference interval; clinical cutoffs, when relevant, are separate sourced thresholds used for a specific purpose.
Results that are clearly outside range, persistent, symptomatic or unexpected should be reviewed by a healthcare professional.
Government medical reference · 2026 · Example adult intervals for ALT, AST, ALP, albumin, bilirubin, total protein, BUN, creatinine and electrolytes · Verified: Aug 12, 2026