Hyperemesis gravidarum

Hyperemesis gravidarum is a severe form of nausea and vomiting in pregnancy that can interfere with daily life and lead to dehydration or weight loss if not monitored. This page gives general information on likely causes, typical signs, diagnostic approaches and when to seek urgent medical attention.

Overview

Hyperemesis gravidarum usually appears in early pregnancy and involves more intense and prolonged vomiting than common pregnancy nausea. While many cases improve after the first trimester, some people experience symptoms longer. The aim here is to raise awareness of the condition and its importance for pregnancy follow-up.

Causes and risk factors

There is no single proven cause. Hormonal changes—particularly higher hCG levels—genetic predisposition and a history of severe nausea in prior pregnancies are commonly associated. Other medical or psychosocial factors may contribute. Identifying personal risk factors helps clinicians tailor monitoring and care.

Symptoms and when to seek urgent care

Concerning signs include persistent vomiting, decreased urine output, rapid weight loss, dizziness or fainting, dark concentrated urine, or inability to keep fluids down. Seek emergency care promptly if there are signs of severe dehydration, fainting, difficulty breathing, high fever, extreme weakness, or a marked decrease in fetal movements.

Diagnosis and follow-up

Diagnosis is usually based on clinical assessment. Health professionals take a detailed history and perform a physical exam, and may order blood tests (electrolytes, kidney function, complete blood count) and urinalysis to check hydration and metabolic status. Ultrasound may be used to assess pregnancy. Follow-up focuses on maintaining fluid and electrolyte balance and monitoring mother and fetus.

Management and supportive measures

Care aims to stabilize overall condition, prevent or treat dehydration, and support nutrition. Clinical teams create individualized follow-up plans and may involve obstetrics (including maternal–fetal medicine), nutrition specialists, or other services as needed. Psychological support and pregnancy counseling can be part of care. If urgent signs appear, contact emergency services or your care team without delay.

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